We have situations at the moment where we are developing larger restructures to paint layouts, while metadata updates/additions are made to sections. These changes are often too large to leave in safe edit for a long time, as it will block any changes needed outside of this.
Currently, you can set a paint layout to safe edit, and allow drafting changes to pages before it gets published and made live. Would love if we could go a step further. Have paint layout changes come under the same protections that Content and Metadata do while in safe-edit — so we could easily test out swapping to new layouts on live content and let our editors preview them before publishing.